SYT Oncology FISH

Leukemia FISH, Lymphoma FISH

12 days

Fluorescence in situ hybridization (FISH)

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Detects SYT gene rearrangement. Used in synovial sarcoma diagnosis.

Fixed-cell pellet from a cytogenetic analysis, slides with metaphases and/or interphase nuclei, OR bone marrow touch prep slides. Whole blood, bone marrow, CSF, FNA, paraffin block are also acceptable with additional charge.

5mL whole blood (pediatric), 3mL bone marrow, fixed-cellpellet from a cytogenetic analysis, 2 slides with metaphaseand/or interphase nuclei, 2 touch preparation slides OR 3 slides from paraffin block

Green-top (sodium heparin) tube; pediatric Vacutainer(R) isoptimal. OR lavender-top (EDTA) tube (suboptimal). For samples with shared karyotype (510999) and any FISH study in the same tube, EDTA is not recommended due to the growth inhibition in cell culture. Adjust tube size to sample volume to avoid heparin toxicity.

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.