Total Protein (TP)

TP

24 hours

Colorimetric

6.4 - 8.3 g/dL (Adults in an ambulatory position, values will be lower in recumbent patients)

The total protein assay is usually used in combination with other tests e.g. albumin (total protein - albumin = globulin fraction).

Note that total protein is included in metabolic panels e.g. CMP (comprehensive metabolic panel) and BMP *basic metabolic panel).

Using this order code, results will be reported in mg/dL.

Accredited NRL Laboratory

Daily

Measurements of total protein are used as an aid in diagnosis and monitoring of a variety of diseases involving the liver, kidney, or bone marrow, as well as other metabolic or nutritional disorders. Plasma proteins are synthesized predominantly in the liver, plasma cells, lymph nodes, spleen and bone marrow. In the course of disease, the total protein concentration and the percentage represented by individual fractions can significantly deviate from normal values. Hypoproteinemia can be caused by diseases and disorders such as loss of blood, nephrotic syndrome, severe burns, salt retention syndrome and Kwashiorkor (acute protein deficiency). Hyperproteinemia can be observed in cases of severe dehydration and illnesses such as multiple myeloma.

Serum or Plasma (Li-Hep)

0.5 mL

Gel-barrier tube or Red-top tube or Green-top (Heparin) tube

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Samples should be sent to the laboratory as soon as possible after collection. If this is not possible, samples should be centrifuged and transported refrigerated (2 to 8°C).