NRAS Gene Mutation Analysis, Extended

11 days

SNaPshot Multiplex PCR (primer extension-based method)

Provide a copy of the pathology report; the NRAS test will be delayed if the pathology report is not received

Accredited Laboratory Partner

Not appplicable

NRAS is a guanosine triphosphate (GTP)-binding protein involved in downstream receptor signaling, which is critical for cell proliferation, survival and differentiation. Mutations in the NRAS oncogene are frequently found in human cancers. They are common in melanomas, colorectal cancer and thyroid cancer. This assay detects NRAS mutations in exons 2, 3 and 4, allowing the determination of drug response.

Formalin-fixed, paraffin-embedded (FFPE) tissue or slides

Formalin-fixed, paraffin-embedded tissue block or four unstained slides and one matching H&E-stained slide at 5 μM

Formalin-fixed, paraffin-embedded (FFPE) tissue blocks or slides