Lipoprotein Analysis (LDL-P, HDL-P, LDL Size), Expanded
7 days
Nuclear magnetic resonance (NMR)
Collect specimen in NMR LipoTube (black-and-yellow-top tube), which is the preferred container. Plain red-top, green-top (heparin-no gel) or lavender-top (EDTA-no gel) tubes also are acceptable. Serum or plasma drawn in gel-barrier collection tubes other than the NMR LipoTube should not be used. The LipoTube is the only acceptable gel-barrier tube. Gently invert tube eight to 10 times to mix contents and allow specimen to clot for 30 minutes upright at room temperature prior to centrifugation (plasma tubes should not clot). Centrifuge specimen within two hours of collection at 1600 to 1800 xg for 10 to 15 minutes to separate serum/plasma from the red cells and to avoid red cell contamination during shipment. If the sample cannot be centrifuged immediately, the sample should be refrigerated (at 2ºC to 8ºC) and centrifuged within 24 hours of collection. Note: Centrifuging the specimen while still cold may negatively affect the migration of the gel to the serum/red cell interface and may increase the likelihood of specimens being contaminated with red cells during shipment. All specimens should be centrifuged by the client prior to shipment to Labcorp to ensure sample integrity. Do not open NMR LipoTube (black-and-yellow-top). Immediately after centrifugation, pipette separated red-top serum or green-top/lavender-top plasma into a transport tube and label accordingly (serum, heparin plasma, EDTA plasma). Keep samples refrigerated until shipment to the laboratory, and ship with frozen cool packs.
Causes for Rejection
Unspun specimens; plasma/serum contaminated with red cells; citrated plasma (light blue-top tube); gross hemolysis; specimen received in inappropriate container; specimen stored at room temperature for more than a total preanalytical time of 24 hours; specimen more than six days old
Accredited Laboratory Partner
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Color graphical report; historical reporting (LDL-P, LDL-C); insulin-resistance score; lipoprotein particle number (LDL-P); particle concentration and size (total HDL-P, small LDL-P, LDL size); standard lipid panel (total cholesterol, calculated LDL cholesterol, HDL cholesterol, triglycerides)
Spun NMR LipoTube (preferred) Serum from a plain red-top tube Plasma from a lavender-top (EDTA-no gel) or green-top (heparin-no gel) tube
2 mL
NMR LipoTube (black-and-yellow-top tube) is the preferred container, plain red-top tube, lavender-top (EDTA-no gel) tube, or green-top (heparin-no gel) tube.
Patient should be fasting for eight hours
Collect and send Sunday to Tuesday only.
| Temperature | Period |
|---|---|
| Refrigerated | 14 days |
| Frozen | 14 days |