O6-Methylguanine-DNA Methyltransferase (MGMT)
14 days
Quantitative methylation-specific polymerase chain reaction (PCR)
Cause for Rejection: Tissue is not primary brain tumor. Tumor block containing insufficient tumor tissue. Tumor fixed in a heavy metal fixative. Broken or stained slides. Decalcified specimens.
Accredited Laboratory Partner
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Assess methylation status of MGMT gene promoter; predicting chemotherapy response in glioblastoma.
Glioblastoma specimens in formalin-fixed paraffin-embedded (FFPE) tissue blocks or Slides
FFPE tissue block or eight unstained slides at 5 μM and one matching H&E slide or nine precut unstained slides from a paraffin block in 5-μM sections
Paraffin tube
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
FFPE tissue block or eight unstained slides at 5 μM and one matching H&E slide or nine precut unstained slides from a paraffin block in 5-μM sections
| Temperature | Period |
|---|---|
| Maintain blocks/slides at Room temperature | Contact Technical Support |