Methotrexate Level

MTX

Up to 24 hours

Homogenous Enzyme Immunoassay

Accredited NRL Laboratory

Daily

Methotrexate is a type of medication called an anti-metabolite, specifically antifolate which inhibits the enzyme Difydrofolate Reductase, which is important for DNA sysnthesis.
It acts as a treatment for rheumatoid arthritis by decreasing immune system activity, for psoriasis by slowing the growth of skin cells and treats cancer by slowing the growth of cancer cells.
Methotrexate is measured to ensure the medication is being cleared appropriately and verifies that a nontoxic concentration has been attained following therapy.

Plasma or Serum

0.5 mL

Serum Separator Tube (SST; Gold Top) Plain Serum Tube (Red Top) Lithium Heparin Plasma (Green Top) EDTA Plasma (Lavender Top)

Seek guidance from your physician prior to sample collection.

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.