Antiphospholipid Syndrome Profile, Clotting Risk Assessment Hypercoagulability Risk, Assessment Thrombosis Risk Assessment
11 days
See individual tests.
Test Includes:
Anticardiolipin Antibodies (ACA), IgA, IgG, IgM Quantitative; Antiphosphatidylserine, IgG and IgM; B2-Glycoprotein 1 Antibodies, IgA, IgG, IgM; Lupus Anticoagulant Reflex; Thrombin Mixing Study
Special Instructions:
If the patient's hematocrit exceeds 55%, the volume of citrate in the collection tube must be adjusted. Refer to Coagulation Collection Procedures for directions.
Causes for Rejection
Gross hemolysis; clotted specimen; frozen specimen thawed in transit; improper labeling
Accredited Laboratory Partner
Contact Technical Support
This profile is designed to detect acquired causes of thrombophilia. Refer to individual test descriptions for more information.
Sodium citrate plasma, frozen, and serum, refrigerated
2.2 mL frozen plasma and 2 mL serum
Blue-top (sodium citrate) tube and gel-barrier or red-top tube
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider. Do not draw from an arm with a heparin lock or heparinized catheter.
Citrated plasma samples should be collected by double centrifugation. Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anti-coagulant with the blood. A discard tube is not required prior to collection of coagulation samples except when using a winged blood collection device (i.e., "butterfly"), in which case a discard tube should be used. When non-citrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternate anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes. Centrifuge for 10 minutes and carefully remove 2/3 of the plasma using a plastic transfer pipette, being careful not to disturb the cells. Deliver to a plastic transport tube, cap and recentifuge for 10 minutes. Use a second plastic pipette to remove plasma, staying clear of the platelets at the bottom of the tube. Transfer the plasma into a Labcorp PP transpak frozen purple tube with screw cap (Labcorp No. 49482). Freeze immediately and maintain frozen until tested. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested. It is important to centrifuge blood samples for plasma collection immediately after collection to separate the plasma from the blood cells. If immediate centrifugation is not possible, collected blood specimens should be kept on ice and centrifuged within an hour.
Serum: If a red-top tube is used, transfer separate serum to a plastic transport tube.
| Temperature | Period |
|---|---|
| Frozen | Contact Technical Support |