C-ANCA, Proteinase 3 Antibodies
5 days
Indirect Immunofluorescence Assay
Accredited NRL Laboratory
Twice per week (Monday and Thursday)
The most common target antigens of ANCA-associated vasculitis are proteinase 3 or myeloperoxidase. Antibodies against proteinase 3 (PR3) are referred to as c-ANCA fluorescent subtype, namely cytoplasmic antibodies (granular cytoplasmic fluorescence). PR3 is a neutral serine proteinase 3, also known as Wegener's autoantigen. Antibodies against PR3 are a highly specific marker in diagnosing Wegener's granulomatosis.
Serum
1 mL
Gel barrier tube (preferred) or red top tube
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.
| Temperature | Period |
|---|---|
| Refrigerated | 2 days |
| Frozen | 7 days |