CYP3A4, CYP3A5
14 days
DNA analysis is performed by allele-specific real-time polymerase chain reactions (RT-PCR) to detect single-nucleotide polymorphisms (SNPs) and insertions within the CYP3A4/3A5 genes and to assign variant CYP3A4 *22 and CYP3A5 *3, *6, and *7 alleles. *1 denotes detection of the reference (wild-type) sequence at the assessed alleles. No other variants in this gene are detected by this assay.
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Analyzes CYP3A4 and 3A5 genes. Affects metabolism of many medications.
Whole Blood or LabCorp buccal swab kit (buccal swab collection kit contains 4 swabs and instructions for use of a buccal swab)
2 mL whole blood or one buccal swab kit (4 swabs)
Lavender-top (EDTA) tube or yellow-top (ACD) tube or LabCorp buccal swab kit.
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.
| Temperature | Period |
|---|---|
| Room temperature | Whole Blood: 28 days Swabs: 2 Months |
| Refrigerated | Whole Blood: 28 days Swabs: Unstable |
| Frozen | Whole Blood: 2 years Swabs: Unstable |