Melanoma, lung, and thyroid cancer, among others. Mutations in V600 mutation codon is of diagnostic importance in hairy cell leukemia, Langerhans cell histiocytosis, and Erdheim-Chester Disease
72 hrs
QPCR
Qualitative detection of V600E/E2/D and V600K/R/M mutations in codon 600 of the BRAF gene
Accredited NRL Laboratory
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Detect somatic BRAF mutations in tumors; personalized cancer treatment.
FFPE, gDNA; Bone Marrow
Formalin-Fixed Paraffin-Embedded tissue block (preferred). 2 scrolls or 5 unstained slides in a sterile container (5 µm sections), along with an H&E-Stained Slide for tumor cell content assessment.DNA extracted from other sample types can also be tested (total DNA should be >50ng with at least 2-5µl provided)
sterile container; EDTA for Bone marrow
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.
| Temperature | Period |
|---|---|
| Room temperature | FFPE & Slides |
| Refrigerated | gDNA: 30 days if Refrigerated or 2 years if Frozen; Bone Marrow: 7 days |