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Angelman and Prader-Willi Syndromes DNA Analysis

Order Code
511210
CPT
81331
Test Details
Synonyms

PWS Methylation Assay

TAT

18 days

Methodology

Methylation-specific PCR and gel electrophoresis

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Genetic test identifying deletions or imprinting defects on chromosome 15. Confirms diagnosis of Angelman or Prader-Willi syndrome.

Specimen Type

Whole Blood LabCorp buccal swab kit (buccal swab collection kit contains instructions for use of a buccal swab) amniotic fluid or cultured amniocytes (Cultured cells are required for testing Direct specimen can be submitted but a culture fee may be included) Note: Submission of maternal Blood is required for fetal testing

Volume

7 mL whole blood, 10 mL amniotic fluid, cultured amniocytes, or LabCorp buccal swab kit

Specimen Container

Lavender-top (EDTA) tube, yellow-top (ACD) tube, sterile plastic conical tube or two confluent T25 flasks for fetal testing, or LabCorp buccal swab kit

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 28 days
Refrigerated 28 days
Order Code
511210
CPT
81331
Test Details
Synonyms

PWS Methylation Assay

TAT

18 days

Methodology

Methylation-specific PCR and gel electrophoresis

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Genetic test identifying deletions or imprinting defects on chromosome 15. Confirms diagnosis of Angelman or Prader-Willi syndrome.

Specimen Type

Whole Blood LabCorp buccal swab kit (buccal swab collection kit contains instructions for use of a buccal swab) amniotic fluid or cultured amniocytes (Cultured cells are required for testing Direct specimen can be submitted but a culture fee may be included) Note: Submission of maternal Blood is required for fetal testing

Volume

7 mL whole blood, 10 mL amniotic fluid, cultured amniocytes, or LabCorp buccal swab kit

Specimen Container

Lavender-top (EDTA) tube, yellow-top (ACD) tube, sterile plastic conical tube or two confluent T25 flasks for fetal testing, or LabCorp buccal swab kit

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 28 days
Refrigerated 28 days