10 days
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
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Evaluates adrenal response to ACTH by measuring androstenedione. Used in congenital adrenal hyperplasia diagnosis.
Serum
1 mL (each specimen), Draw blood for baseline androstenedione. Inject cosyntropin 250 ug IM or IV (if IV, dilute cosyntropin in 2-5 mL of sterile saline and inject over two minutes). Draw blood for stimulated androstenedione 60 minutes after.
Red-top tube
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
Do not use a gel-barrier tube.
| Temperature | Period |
|---|---|
| Room temperature | 14 days |
| Refrigerated | 14 days |
| Frozen | 14 days |