5-hydroxyindoleacetic acid
12 days
Liquid chromatography/tandem mass spectrometry (LC/MS-MS)
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Measures 5-hydroxyindoleacetic acid in urine to diagnose carcinoid tumors. Reflects serotonin metabolism.
24 hour urine
4 mL aliquot
Plastic urine container, no preservative.
Measure and record total 24-hour urine volume on the request form. Patient Preparation Avoid bananas, avocados, plums, eggplant, tomatoes, avocados plums, eggplant, tomatoes, plantain, pineapple, walnuts, and interfering drugs for a 72 hour period prior to and during collection. Foods and medications associated with altered urinary HIAA results: Decreased HIAA: Aspirin, chlorpromazine (Thorazine), corticotropin, dihydroxyphenylacetic acid, alcohol, gentisic acid, homogentisic acid, hydrazine derivatives, imipramine (Tofranil®),
This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.
| Temperature | Period |
|---|---|
| Room temperature | 7 days |
| Refrigerated | 14 days |
| Frozen | 14 days |
| Freeze/thaw cycles | Stable x3 |