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Protein S Deficiency Profile

Order Code
117754
CPT
85305, 85306x2
Test Details
TAT

7 days

Methodology

Total PS and free PS antigen: Total PS and free PS antigens are measured by latex immunoassay (IA). PS activity: The patient plasma is added to PS-depleted normal plasma with normal levels of all factors but PS. The mixture is supplemented with excess aPC, and factor V is then added. The extent of prolongation of the time to clot formation after calcium chloride is added is proportional to plasma PS activity.

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Includes protein S antigen and activity. Used in hypercoagulability workup.

Specimen Type

Plasma

Volume

1 mL

Specimen Container

Blue top (sodium citrate) tube

Patient Preparation

Avoid warfarin (Coumadin®) therapy for two weeks and heparin therapy for two days prior to the test. Do not draw from an arm with a heparin lock or heparinized catheter.

Collection

Citrated Plasma samples should be collected by double centrifugation

Specimen Stability
Temperature Period
Frozen 28 days
Freeze/thaw cycles Stable x3
Order Code
117754
CPT
85305, 85306x2
Test Details
TAT

7 days

Methodology

Total PS and free PS antigen: Total PS and free PS antigens are measured by latex immunoassay (IA). PS activity: The patient plasma is added to PS-depleted normal plasma with normal levels of all factors but PS. The mixture is supplemented with excess aPC, and factor V is then added. The extent of prolongation of the time to clot formation after calcium chloride is added is proportional to plasma PS activity.

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Includes protein S antigen and activity. Used in hypercoagulability workup.

Specimen Type

Plasma

Volume

1 mL

Specimen Container

Blue top (sodium citrate) tube

Patient Preparation

Avoid warfarin (Coumadin®) therapy for two weeks and heparin therapy for two days prior to the test. Do not draw from an arm with a heparin lock or heparinized catheter.

Collection

Citrated Plasma samples should be collected by double centrifugation

Specimen Stability
Temperature Period
Frozen 28 days
Freeze/thaw cycles Stable x3