Acute Lymphocytic Leukemia (ALL), Pediatric
9 days
Fluorescence in situ hybridization (FISH)
Test Includes: Fluorescence in situ hybridization (FISH) for acute lymphoblastic leukemia (ALL), targeting rearrangement of BCR-ABL, TCF3, KMT2A (mLL), ETV6/RUNX1, and numerical changes of 4, 10, 17, and CDKN2A deletion.
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FISH panel detecting chromosomal abnormalities in pediatric ALL.
Whole blood, bone marrow, CSF, fixed-cell pellet from a cytogenetic analysis, slide with metaphase and/or interphase nuclei OR bone marrow touch preparation slides are acceptable for testing
5mL whole blood (pediatric), 3mL bone marrow, fixed-cellpellet from a cytogenetic analysis, 12 slides with metaphase and/or interphase nuclei OR 12 touch preparation slides
Green-top (sodium heparin) tube; pediatric Vacutainer(R) isoptimal. OR lavendar-top (EDTA) tube (suboptimal).
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
For samples with shared karyotype (510999) and any FISH studyin the same tube, EDTA is not recommended due to the growthinhibition in cell culture. Adjust tube size to sample
| Temperature | Period |
|---|---|
| Room temperature | Contact Technical Support |