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Pediatric Acute Lymphoblastic Leukemia (ALL) Profile FISH

Order Code
510324
CPT
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Test Details
Synonyms

Acute Lymphocytic Leukemia (ALL), Pediatric

TAT

9 days

Methodology

Fluorescence in situ hybridization (FISH)

Remarks

Test Includes: Fluorescence in situ hybridization (FISH) for acute lymphoblastic leukemia (ALL), targeting rearrangement of BCR-ABL, TCF3, KMT2A (mLL), ETV6/RUNX1, and numerical changes of 4, 10, 17, and CDKN2A deletion.

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

FISH panel detecting chromosomal abnormalities in pediatric ALL.

Specimen Type

Whole blood, bone marrow, CSF, fixed-cell pellet from a cytogenetic analysis, slide with metaphase and/or interphase nuclei OR bone marrow touch preparation slides are acceptable for testing

Volume

5mL whole blood (pediatric), 3mL bone marrow, fixed-cellpellet from a cytogenetic analysis, 12 slides with metaphase and/or interphase nuclei OR 12 touch preparation slides

Specimen Container

Green-top (sodium heparin) tube; pediatric Vacutainer(R) isoptimal. OR lavendar-top (EDTA) tube (suboptimal).

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

For samples with shared karyotype (510999) and any FISH studyin the same tube, EDTA is not recommended due to the growthinhibition in cell culture. Adjust tube size to sample

Specimen Stability
Temperature Period
Room temperature Contact Technical Support
Order Code
510324
CPT
Contact Technical Support
Test Details
Synonyms

Acute Lymphocytic Leukemia (ALL), Pediatric

TAT

9 days

Methodology

Fluorescence in situ hybridization (FISH)

Remarks

Test Includes: Fluorescence in situ hybridization (FISH) for acute lymphoblastic leukemia (ALL), targeting rearrangement of BCR-ABL, TCF3, KMT2A (mLL), ETV6/RUNX1, and numerical changes of 4, 10, 17, and CDKN2A deletion.

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

FISH panel detecting chromosomal abnormalities in pediatric ALL.

Specimen Type

Whole blood, bone marrow, CSF, fixed-cell pellet from a cytogenetic analysis, slide with metaphase and/or interphase nuclei OR bone marrow touch preparation slides are acceptable for testing

Volume

5mL whole blood (pediatric), 3mL bone marrow, fixed-cellpellet from a cytogenetic analysis, 12 slides with metaphase and/or interphase nuclei OR 12 touch preparation slides

Specimen Container

Green-top (sodium heparin) tube; pediatric Vacutainer(R) isoptimal. OR lavendar-top (EDTA) tube (suboptimal).

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

For samples with shared karyotype (510999) and any FISH studyin the same tube, EDTA is not recommended due to the growthinhibition in cell culture. Adjust tube size to sample

Specimen Stability
Temperature Period
Room temperature Contact Technical Support