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MLH1/MSH2/MSH6/PMS2/EPCAM Somatic Tumor Mismatch Repair Sequencing and Deletion/Duplication Test

Order Code
481472
CPT
81445, 88381
Test Details
Synonyms

EPCAM, Hereditary Nonpolyposis Colorectal Cancer, Mismatch Repair Somatic, IMCAN Tumor

TAT

32 days

Methodology

Next generation sequencing (NGS), Multiplex Ligation-Dependent Probe Amplification (mLPA), Sanger sequencing

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Comprehensive tumor analysis for mismatch repair genes. Used in Lynch syndrome and MSI-high tumor identification.

Specimen Type

Formalin fixed paraffin-embedded (FFPE) tissue Whole Blood  

Volume

Formalin fixed paraffin embedded (FFPE) block (preferred) or 19 serial unstained unbaked slides (5-10 microns thick) with 1 adjacent unstained unbaked slide (4 microns thick), Whole Blood: 8.5 mL

Specimen Container

Lavender-top (EDTA) tube, yellow-top (ACD) tube, blocks or slides

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

Whole blood samples must be received at Impact Genetics within five days of collection

Specimen Stability
Temperature Period
Room temperature 5 days
Order Code
481472
CPT
81445, 88381
Test Details
Synonyms

EPCAM, Hereditary Nonpolyposis Colorectal Cancer, Mismatch Repair Somatic, IMCAN Tumor

TAT

32 days

Methodology

Next generation sequencing (NGS), Multiplex Ligation-Dependent Probe Amplification (mLPA), Sanger sequencing

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Comprehensive tumor analysis for mismatch repair genes. Used in Lynch syndrome and MSI-high tumor identification.

Specimen Type

Formalin fixed paraffin-embedded (FFPE) tissue Whole Blood  

Volume

Formalin fixed paraffin embedded (FFPE) block (preferred) or 19 serial unstained unbaked slides (5-10 microns thick) with 1 adjacent unstained unbaked slide (4 microns thick), Whole Blood: 8.5 mL

Specimen Container

Lavender-top (EDTA) tube, yellow-top (ACD) tube, blocks or slides

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

Whole blood samples must be received at Impact Genetics within five days of collection

Specimen Stability
Temperature Period
Room temperature 5 days