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Methylmalonic Acid, Quantitative

Order Code
99121025
CPT
83921
Test Details
Synonyms

MMA

TAT

7 days (15 days for repeat testing)

Methodology

Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS)

Performing Location

Accredited NRL Laboratory

Testing Frequency

Monday to Friday

Test Overview

Measures the concentration of methylmalonic acid (MMA) in the blood or urine. Elevated levels are a sensitive indicator of vitamin B12 (cobalamin) deficiency and certain inborn errors of metabolism (e.g., methylmalonic acidemia).

Specimen Type

Serum or Plasma

Volume

1 mL

Specimen Container

Serum (Red-top tube, gel-barrier tube) or Plasma heparin anticoagulant (green-top)

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 7 days
Refrigerated 180 days
Frozen 360 days
Order Code
99121025
CPT
83921
Test Details
Synonyms

MMA

TAT

7 days (15 days for repeat testing)

Methodology

Liquid Chromatography with Tandem Mass Spectrometry (LC-MS/MS)

Performing Location

Accredited NRL Laboratory

Testing Frequency

Monday to Friday

Test Overview

Measures the concentration of methylmalonic acid (MMA) in the blood or urine. Elevated levels are a sensitive indicator of vitamin B12 (cobalamin) deficiency and certain inborn errors of metabolism (e.g., methylmalonic acidemia).

Specimen Type

Serum or Plasma

Volume

1 mL

Specimen Container

Serum (Red-top tube, gel-barrier tube) or Plasma heparin anticoagulant (green-top)

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 7 days
Refrigerated 180 days
Frozen 360 days