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Factor XI Inhibitor Profile Comprehensive

Order Code
500396
CPT
85270, 85335, 85730, 85732x3
Test Details
Synonyms

Bethesda Titer

TAT

9 days

Methodology

The factor XI inhibitor (Bethesda Titer) assay is performed using an activated partial thromboplastin time (aPTT)-based test system.

Remarks

Test Includes: Activated partial thromboplastin time (aPTT), aPTT 1:1 mix with normal plasma, aPTT 1:1 mix with saline, factor XI activity, factor XI Bethesda titer

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Evaluates for the presence of inhibitors (autoantibodies) against Factor XI. Used in patients with acquired Factor XI deficiency, unexplained prolonged aPTT, or bleeding despite normal antigen levels. Helps differentiate between inherited and acquired causes of bleeding.

Specimen Type

Plasma

Volume

6 mL (2 mL in each of 3 tubes)

Specimen Container

Blue top (sodium citrate) tube

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

Citrated Plasma samples should be collected by double centrifugation

Specimen Stability
Temperature Period
Frozen Contact Technical Support
Order Code
500396
CPT
85270, 85335, 85730, 85732x3
Test Details
Synonyms

Bethesda Titer

TAT

9 days

Methodology

The factor XI inhibitor (Bethesda Titer) assay is performed using an activated partial thromboplastin time (aPTT)-based test system.

Remarks

Test Includes: Activated partial thromboplastin time (aPTT), aPTT 1:1 mix with normal plasma, aPTT 1:1 mix with saline, factor XI activity, factor XI Bethesda titer

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Evaluates for the presence of inhibitors (autoantibodies) against Factor XI. Used in patients with acquired Factor XI deficiency, unexplained prolonged aPTT, or bleeding despite normal antigen levels. Helps differentiate between inherited and acquired causes of bleeding.

Specimen Type

Plasma

Volume

6 mL (2 mL in each of 3 tubes)

Specimen Container

Blue top (sodium citrate) tube

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

Citrated Plasma samples should be collected by double centrifugation

Specimen Stability
Temperature Period
Frozen Contact Technical Support