Comprehensive Chromosomal Profiling by sWGS
7 days
sWGS
Accredited NRL Laboratory
Twice a week
Shallow Whole Genome Sequencing (sWGS) enables genome-wide detection of chromosomal gains and losses from uncultured bone marrow samples. This approach can detect whole-chromosome aneuploidies (e.g., monosomies, trisomies) as well as clinically relevant deletions and gains/amplifications, including: 1p, 1q, del(5q), del(7q), trisomy 8, del(20q), del(11q), del(13q), and del(17p) involving the TP53 locus. This comprehensive assay eliminates the need for both karyotyping and FISH testing. Test Limitations: sWGS cannot detect balanced chromosomal rearrangements (e.g., translocations/gene fusions, inversions) and cannot reliably identify microdeletions or microduplications smaller than ~10 Mb.
Bone Marrow aspirate or Whole blood (well-mixed to prevent clotting)
Bone marrow 2 to 3 mL, Wole blood 6 mL
Sodium or Lithium heparin (green top) tube
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.
| Temperature | Period |
|---|---|
| Room temperature | 48 hours |
Comprehensive Chromosomal Profiling by sWGS
7 days
sWGS
Accredited NRL Laboratory
Twice a week
Shallow Whole Genome Sequencing (sWGS) enables genome-wide detection of chromosomal gains and losses from uncultured bone marrow samples. This approach can detect whole-chromosome aneuploidies (e.g., monosomies, trisomies) as well as clinically relevant deletions and gains/amplifications, including: 1p, 1q, del(5q), del(7q), trisomy 8, del(20q), del(11q), del(13q), and del(17p) involving the TP53 locus. This comprehensive assay eliminates the need for both karyotyping and FISH testing. Test Limitations: sWGS cannot detect balanced chromosomal rearrangements (e.g., translocations/gene fusions, inversions) and cannot reliably identify microdeletions or microduplications smaller than ~10 Mb.
Bone Marrow aspirate or Whole blood (well-mixed to prevent clotting)
Bone marrow 2 to 3 mL, Wole blood 6 mL
Sodium or Lithium heparin (green top) tube
No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.
This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.
| Temperature | Period |
|---|---|
| Room temperature | 48 hours |