NfL, AB 42/40 ratio, Total tau, p-Tau-181, (Reflex) Neurogranin
16 days
Simoa® assay or Lumipulse® assay
Tests included:
Neurofilament Light Chain (NfL), CSF, CLEIA
Amyloid-beta 42/40 Ratio (Aβ42/40), CSF, CLEIA
Total Tau (t-Tau), CSF, CLEIA
Phosphorylated Tau 181 (p-Tau 181), CSF, CLEIA
Neurogranin (Reflex), CSF, ELISA
Accredited Laboratory Partner
Weekly
This panel is useful in patients being assessed for Alzheimer disease and other causes of neurological decline. Based on results obtained, neurogranin (associated with the pathogenesis of a wide range of neurological conditions) will be performed.
CSF
2 mL
Sterile container
Samples should be collected following overnight fasting. If patients are taking biotin (Vitamin B7), they should stop taking it 72 hours prior to sample collection.
Transport to the laboratory immediately following collection.
| Temperature | Period |
|---|---|
| Room temperature | 2 days |
| Frozen | 2 months at -20° C |
NfL, AB 42/40 ratio, Total tau, p-Tau-181, (Reflex) Neurogranin
16 days
Simoa® assay or Lumipulse® assay
Tests included:
Neurofilament Light Chain (NfL), CSF, CLEIA
Amyloid-beta 42/40 Ratio (Aβ42/40), CSF, CLEIA
Total Tau (t-Tau), CSF, CLEIA
Phosphorylated Tau 181 (p-Tau 181), CSF, CLEIA
Neurogranin (Reflex), CSF, ELISA
Accredited Laboratory Partner
Weekly
This panel is useful in patients being assessed for Alzheimer disease and other causes of neurological decline. Based on results obtained, neurogranin (associated with the pathogenesis of a wide range of neurological conditions) will be performed.
CSF
2 mL
Sterile container
Samples should be collected following overnight fasting. If patients are taking biotin (Vitamin B7), they should stop taking it 72 hours prior to sample collection.
Transport to the laboratory immediately following collection.
| Temperature | Period |
|---|---|
| Room temperature | 2 days |
| Frozen | 2 months at -20° C |