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BCR-ABL1 Kinase Domain Mutation Analysis

Order Code
480510
CPT
81170
Test Details
Synonyms

ABL1 Mutation Analysis for Resistance to Imatinib Mesylate

TAT

18 days

Methodology

Polymerase chain reaction (PCR), direct sequencing, capillary electrophoresis

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Identifies mutations in the BCR-ABL1 gene. Used to evaluate resistance to tyrosine kinase inhibitors in CML.

Specimen Type

Whole Blood or Bone Marrow

Volume

3 to 5 mL whole blood or 1 to 2 mL bone marrow

Specimen Container

Lavender-top (EDTA) tube, green-top (sodium heparin) tube, yellow-top (ACD-A) tube, tan-top (K2-EDTA) tube or pink-top (K2-EDTA) tube

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 2 days
Order Code
480510
CPT
81170
Test Details
Synonyms

ABL1 Mutation Analysis for Resistance to Imatinib Mesylate

TAT

18 days

Methodology

Polymerase chain reaction (PCR), direct sequencing, capillary electrophoresis

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Identifies mutations in the BCR-ABL1 gene. Used to evaluate resistance to tyrosine kinase inhibitors in CML.

Specimen Type

Whole Blood or Bone Marrow

Volume

3 to 5 mL whole blood or 1 to 2 mL bone marrow

Specimen Container

Lavender-top (EDTA) tube, green-top (sodium heparin) tube, yellow-top (ACD-A) tube, tan-top (K2-EDTA) tube or pink-top (K2-EDTA) tube

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 2 days