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B-Cell, IGK Gene Rearrangements

Order Code
480812
CPT
81264
Test Details
Synonyms

IGK Gene Clonality Assay

TAT

11 days

Methodology

Polymerase chain reaction (PCR)

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Detects clonality in kappa light chain genes. Supports diagnosis of B-cell proliferative disorders.

Specimen Type

Whole Blood, Bone Marrow, formalin-fixed paraffin-embedded (FFPE) tissue block or Slides fresh or Frozen tissue

Volume

3 to 5 mL whole blood, 1 mL bone marrow, five unstained slides at 10 μM or formalin-fixed, paraffin-embedded tissue block, tissue in RPMI or frozen

Specimen Container

Lavender-top (EDTA) tube, yellow-top (ACD) tube, green-top (heparin) tube, tan-top (K2-EDTA) tube and pink-top (K2-EDTA) tube, FFPE tissue block or slides, tissue in RPMI or frozen

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

Fresh tissue should be placed in RPMI medium or shipped frozen on dry ice. Small samples (e.g., punch biopsies, fine-needle aspirates) will also be accepted. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate specimens for each test requested.

Specimen Stability
Temperature Period
Refrigerated blood, bone marrow or tissue in RPMI
Frozen Tissue
Order Code
480812
CPT
81264
Test Details
Synonyms

IGK Gene Clonality Assay

TAT

11 days

Methodology

Polymerase chain reaction (PCR)

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Detects clonality in kappa light chain genes. Supports diagnosis of B-cell proliferative disorders.

Specimen Type

Whole Blood, Bone Marrow, formalin-fixed paraffin-embedded (FFPE) tissue block or Slides fresh or Frozen tissue

Volume

3 to 5 mL whole blood, 1 mL bone marrow, five unstained slides at 10 μM or formalin-fixed, paraffin-embedded tissue block, tissue in RPMI or frozen

Specimen Container

Lavender-top (EDTA) tube, yellow-top (ACD) tube, green-top (heparin) tube, tan-top (K2-EDTA) tube and pink-top (K2-EDTA) tube, FFPE tissue block or slides, tissue in RPMI or frozen

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

Fresh tissue should be placed in RPMI medium or shipped frozen on dry ice. Small samples (e.g., punch biopsies, fine-needle aspirates) will also be accepted. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate specimens for each test requested.

Specimen Stability
Temperature Period
Refrigerated blood, bone marrow or tissue in RPMI
Frozen Tissue