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Adult Acute Lymphoblastic Leukemia (ALL) Profile FISH

Order Code
511077
CPT
88271x8, 88275x4
Test Details
Synonyms

Acute Lymphoblastic Leukemia; Leukemia/Lymphoma-specific FISH

TAT

9 days

Methodology

Fluorescence in situ hybridization (FISH)

Remarks

Test Includes:
Fluorescence in situ hybridization (FISH) for acute lymphoblastic leukemia (ALL), targeting rearrangement of BCR/ABL, KMT2A (mLL), CMYC and numerical changes of chromosome 6 and 21q deletion

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Uses FISH to detect chromosomal abnormalities in ALL. Aids in diagnosis, risk stratification, and treatment planning.

Specimen Type

Blood, Bone Marrow, CSF fixed-cell pellet from a cytogenetic analysis slide with metaphase and/or interphase nuclei or Bone Marrow touch preparation Slides are acceptable for testing

Volume

10 mL blood (pediatric), 3 mL bone marrow, fixed-cell pellet from a cytogenetic analysis, 8 slides with metaphase and/or interphase nuclei or 8 touch preparation slides.

Specimen Container

Green-top (sodium heparin) tube, pediatric Vacutainer® is optimal or lavender-top (EDTA) tube (suboptimal). Adjust tube size to sample volume to avoid heparin toxicity.

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 7 days
Order Code
511077
CPT
88271x8, 88275x4
Test Details
Synonyms

Acute Lymphoblastic Leukemia; Leukemia/Lymphoma-specific FISH

TAT

9 days

Methodology

Fluorescence in situ hybridization (FISH)

Remarks

Test Includes:
Fluorescence in situ hybridization (FISH) for acute lymphoblastic leukemia (ALL), targeting rearrangement of BCR/ABL, KMT2A (mLL), CMYC and numerical changes of chromosome 6 and 21q deletion

Performing Location

Accredited Laboratory Partner

Testing Frequency

Contact Technical Support

Test Overview

Uses FISH to detect chromosomal abnormalities in ALL. Aids in diagnosis, risk stratification, and treatment planning.

Specimen Type

Blood, Bone Marrow, CSF fixed-cell pellet from a cytogenetic analysis slide with metaphase and/or interphase nuclei or Bone Marrow touch preparation Slides are acceptable for testing

Volume

10 mL blood (pediatric), 3 mL bone marrow, fixed-cell pellet from a cytogenetic analysis, 8 slides with metaphase and/or interphase nuclei or 8 touch preparation slides.

Specimen Container

Green-top (sodium heparin) tube, pediatric Vacutainer® is optimal or lavender-top (EDTA) tube (suboptimal). Adjust tube size to sample volume to avoid heparin toxicity.

Patient Preparation

No special preparation is required for this test. You may eat, drink, and take your medications as normal, unless instructed otherwise by your healthcare provider.

Collection

This test does not require any special collection or pre-analytical handling. Follow routine specimen collection protocols.

Specimen Stability
Temperature Period
Room temperature 7 days