Our Center of Excellence for Specialized Coagulation Testing is located at NRL’s laboratory in ICAD, Abu Dhabi. The laboratory provides comprehensive specialized testing for coagulation disorders and was set up with the support of world-class experts from Colorado Coagulation, part of LabCorp’s specialty laboratory network.

Below please find more information about the test menu of the Center.

 Order Code  Order Code Name  CPT Code  Volume  Specimen stability

 086231

 Factor II Activity, Plasma

 85210

 2mL

 4 weeks if frozen @ -80° C

 086249

 Factor V Activity, Plasma

 85220

 2mL

 4 weeks if frozen @ -80° C

 800599

 Factor VII Activity, Plasma

 85230

 2mL

 4 weeks if frozen @ -80° C

 086264

 Factor VIII Activity, Plasma

 85240

 2mL

 2 weeks if frozen @ -80° C

 086298

 Factor IX Activity, Plasma

 85250

 2mL

 2 weeks if frozen@ -80° C

 086306

 Factor X Activity, Plasma

 85260

 2mL

 4 weeks if frozen @ -80° C

 086314

 Factor XI Activity, Plasm

 85270

 2mL

 2 weeks if frozen @ -80° C

 086322

 Factor XII Activity, Plasma

 85280

 2mL

 2 weeks if frozen @ -80° C

 500463 

 Protein C Activity, Plasma

 85303

 2mL

 4 weeks if frozen @ -20° C

 164519

 Protein S, Free Antigen, Plasma

 85306

 2mL

 3 months if frozen @ -20° C

 015230

 Thrombin Time, Plasma

 85670

 2mL

 4 weeks if frozen @ -80° C

 117892

 Lupus Anticoagulant with Reflex, Plasma

 85613
 85732

 3mL

 2 weeks if frozen @ -80° C

 

Specimen type: Citrated plasma

Specimen Container: Blue-top tube containing 3.2% buffered sodium citrate

Storage: Freeze -20° C

TAT: 3-5 days

Collection and Processing of Coagulation Specimens

The accuracy of coagulation testing results is highly dependent upon the integrity of the sample. To ensure the best possible specimen, please follow the collection requirements and instructions as closely as possible.  Adherence to these guidelines will improve quality and reliable of the coagulation test results.

Clinical Significance

Specialized coagulation is state-of-the-art testing performed for the diagnosis of thrombosis and hemostasis disorders to enhance diagnostic capabilities for congenital, acquired or autoimmune coagulation disorders. Bleeding issues may be associated with a wide variety of coagulation abnormalities or may be due to trauma or surgery.  Routine clotting tests comprise of the prothrombin time (PT), fibrinogen, activated partial thromboplastin time (APTT), thrombin time and D-Dimer.  Abnormal clotting results that cannot be explained in the clinical context are investigated further with “specialized coagulation” tests.  These tests are performed by modifications of PT or APTT assays, using several plasma dilutions, in order to pinpoint specific factor deficiencies (e.g., FVIII or FIX in classical haemophilia).  Testing also includes the identification of specific factor deficiencies involved in the clotting complex cascade (intrinsic and extrinsic pathway).  Additional testing such as Protein C and protein S, Lupus anticoagulant testing is available to help to investigate a possible excessive clotting (hypercoagulable) disorder and/or to help diagnose the cause of an inappropriate blood clot such as deep venous thrombosis (DVT) or a venous thromboembolism (VTE).

2017 Sample Collection and Processing Instuctions for Coagulation Testing