Our Center of Excellence for Specialized Coagulation Testing is located at NRL’s laboratory in ICAD, Abu Dhabi. The laboratory provides comprehensive specialized testing for coagulation disorders and was set up with the support of world-class experts from Colorado Coagulation, part of LabCorp’s specialty laboratory network.

Below please find more information about the test menu of the Center.

 

Order Code  Order Code Name  CPT Code  Volume  Specimen stability Specimen Type Storage TAT Specimen Container
 086231 Factor II Activity, Plasma  85210  2mL  4 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 086249 Factor V Activity, Plasma  85220  2mL  4 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 800599 Factor VII Activity, Plasma  85230  2mL  4 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 086264 Factor VIII Activity, Plasma  85240  2mL  2 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 086298 Factor IX Activity, Plasma  85250  2mL  2 weeks if frozen@ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 086306 Factor X Activity, Plasma  85260  2mL  4 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 086314 Factor XI Activity, Plasm  85270  2mL  2 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 086322 Factor XII Activity, Plasma  85280  2mL  2 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 500463  Protein C Activity, Plasma  85303  2mL  4 weeks if frozen @ -20° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 164519 Protein S, Free Antigen, Plasma  85306  2mL  3 months if frozen @ -20° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 015230 Thrombin Time, Plasma  85670  2mL  4 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
 117892 Lupus Anticoagulant with Reflex, Plasma  85613
 85732
 3mL  2 weeks if frozen @ -80° C Citrated Plasma Freeze -20° C 3-5 days Blue-top (sodium citrate) tube
164509 von Willebrand Factor (vWF) Activity  85245 1.0 mL 2 weeks in   -80C Citrated Plasma Frozen 2-5 days Blue-top (sodium citrate) tube
86280 von Willebrand Factor (vWF) Antigen 85246 1.0 mL 2 weeks in   -80C Citrated Plasma Frozen 2-5 days Blue-top (sodium citrate) tube
15040 Antithrombin Activity 85300 1.0 mL 2 weeks in   -80C Citrated Plasma Frozen 2-5 days Blue-top (sodium citrate) tube
4804 Ionized Calcium 82330 0.5 mL 30 mins open tube
2 weeks unopen tube
Serum Refrigerate 1 day Red top tube or Gel Barrier tube Collection: Centrifuge and send unopened gel –barrier tube with vacuum intact.

 

Collection and Processing of Coagulation Specimens

The accuracy of coagulation testing results is highly dependent upon the integrity of the sample. To ensure the best possible specimen, please follow the collection requirements and instructions as closely as possible.  Adherence to these guidelines will improve quality and reliable of the coagulation test results.

Clinical Significance

Specialized coagulation is state-of-the-art testing performed for the diagnosis of thrombosis and hemostasis disorders to enhance diagnostic capabilities for congenital, acquired or autoimmune coagulation disorders. Bleeding issues may be associated with a wide variety of coagulation abnormalities or may be due to trauma or surgery.  Routine clotting tests comprise of the prothrombin time (PT), fibrinogen, activated partial thromboplastin time (APTT), thrombin time and D-Dimer.  Abnormal clotting results that cannot be explained in the clinical context are investigated further with “specialized coagulation” tests.  These tests are performed by modifications of PT or APTT assays, using several plasma dilutions, in order to pinpoint specific factor deficiencies (e.g., FVIII or FIX in classical haemophilia).  Testing also includes the identification of specific factor deficiencies involved in the clotting complex cascade (intrinsic and extrinsic pathway).  Additional testing such as Protein C and protein S, Lupus anticoagulant testing is available to help to investigate a possible excessive clotting (hypercoagulable) disorder and/or to help diagnose the cause of an inappropriate blood clot such as deep venous thrombosis (DVT) or a venous thromboembolism (VTE).

2017 Sample Collection and Processing Instuctions for Coagulation Testing